Granular gel bone substitutes
are a mixture of cortical-cancellous granules (Bio-Gen Mix), and water-based gel.
 
The standard granule size
0.5 – 1 mm is correct for most indications.
 
The mixture contains
spongy granules, which remodel in 4-6 months, and cortical granules that remodel in 8-12 months.
 
The advantage of the gel format
is the smaller probability of contamination of the graft, since the hydration step is not necessary.